Oral Administration of p-Hydroxycinnamic Acid Attenuates Atopic Dermatitis by Downregulating Th1 and Th2 Cytokine Production and Keratinocyte Activation.
Atopic dermatitis (AD) is a complex disease that is caused by various factors, including environmental change, genetic KIDS FOOTWEAR defects, and immune imbalance.We previously showed that p-hydroxycinnamic acid (HCA) isolated from the roots of Curcuma longa inhibits T-cell activation without inducing cell death.Here, we demonstrated that oral admi